all-trans-retinol/Finding
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Increases hip fracture incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“High intake of vitamin A and retinol were shown to increase risk of hip fracture (adj.RR [95% CI] = 1.29 [1.07, 1.57] and 1.40 [1.03, 1.91], respectively), whereas beta-carotene intake was not found to increase the risk of hip fracture (adj.RR [95% CI] = 0.82 [0.59, 1.14]).”
Quoted verbatim from The relationship between vitamin A and risk of fracture: meta-analysis of prospective studies.. - Study
- meta-analysis
- Population
- Prospective cohort studies of dietary retinol intake (eight vitamin A, retinol or beta-carotene intake studies pooled); high versus low intake
Effect 1.4 risk ratio, 95% CI 1.03 to 1.91
The relationship between vitamin A and risk of fracture: meta-analysis of prospective studies.2014PMID:24700407Permalink
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To cite this finding: https://catalystproject.ai/e/01M5KYP36B185XF9R6NZQMPG5K