L-ascorbic acid/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases C-reactive protein concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“When compared to the control group, the ASTRALI group at T96 showed significantly higher median of IL-10 (31.6 ± 25.8 vs 17.7 ± 12.0 pg/mL, P < .0001) levels and superoxide dismutase (12 876 ± 4627 U/L vs 5895 ± 6632 U/L, P < .0001) activities, and lower median C-reactive protein (76 ± 50 vs 89 ± 56 mg/L, P = .033), IL-8 (11.8 ± 7.3 vs 35.5 ± 19.8 pg/mL, P < .0001) and malondialdehyde (0.197 ± 0.034 vs 0.234 ± 0.074 μM/L, P = .002) levels.”
Quoted verbatim from Role of ascorbic acid infusion in critically ill patients with transfusion-related acute lung injury.. - Study
- RCT
- Duration
- 4 days
- Dose
- 2.5 g every 6 h intravenous vitamin C for 96 hours
- Population
- Critically ill patients with transfusion-related acute lung injury (TRALI), at end of treatment (T96)
Role of ascorbic acid infusion in critically ill patients with transfusion-related acute lung injury.2022PMID:34866234Permalink
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To cite this finding: https://catalystproject.ai/e/01M5JFP13XK208MNJXNJ809SXP