L-ascorbic acid/Finding
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Inhibits FMO5
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“In conclusion, ascorbate blocks the stimulation by septic insult of redox-sensitive Jak2/Stat1/IRF1 signaling, p47phox expression, and NADPH oxidase activity in microvascular endothelial cells.”
Quoted verbatim from Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells.. - Study
- in vitro · not in humans
- Population
- mouse microvascular endothelial cells of skeletal muscle origin exposed to lipopolysaccharide and interferon-gamma
Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells.2007PMID:17157199Permalink
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To cite this finding: https://catalystproject.ai/e/01M4QKAXRMFWC7S1TK60F7GHD7