L-ascorbic acid/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on incidence of cardiovascular disease (composite)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“There was no effect of vitamin C on the primary endpoint of major cardiovascular events (HR, 0.99; 95% CI, 0.89–1.11; P=0.91) (Table 2).”
Quoted verbatim from Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial.. - Study
- RCT
- Dose
- 500 mg synthetic ascorbic acid daily
- Population
- 14,641 US male physicians aged 50 years or older; vitamin E, multivitamin and beta-carotene were randomised independently in a factorial design and balanced across the vitamin C and placebo arms
Effect 0.99 hazard ratio, 95% CI 0.89 to 1.11
Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial.2008PMID:18997197Industry fundedPermalink
Keep reading
- Everything the graph holds on L-ascorbic acid
- Every compound studied against Incidence of cardiovascular disease (composite)
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M4QHR0KGKMTAC4ZYKMNF1RJ9