selenium atom/Finding
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Decreases serum thyroid peroxidase antibody (TPOAb) titre
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“We found that the TPOAb levels of HT patients who received Se supplementation decreased significantly after 3 months (SMD = −0.46, 95% CI: −0.74 to −0.18, P =.001) and after 6 months (SMD = −0.80, 95% CI: −1.38 to −0.21, P =.008).”
Quoted verbatim from Clinical efficacy of selenium supplementation in patients with Hashimoto thyroiditis: A systematic review and meta-analysis.. - Study
- meta-analysis
- Dose
- typically 200 μg/d
- Population
- Adults with Hashimoto thyroiditis, with or without levothyroxine; selenium (selenomethionine, selenoyeast or sodium selenate) against placebo, no treatment or levothyroxine alone; 6-month timepoint estimate recorded
Effect -0.8 standardised mean difference, 95% CI -1.38 to -0.21
Clinical efficacy of selenium supplementation in patients with Hashimoto thyroiditis: A systematic review and meta-analysis.2025PMID:40898469Permalink
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- Every compound studied against Serum thyroid peroxidase antibody (TPOAb) titre
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To cite this finding: https://catalystproject.ai/e/01M4QGQ6ZFA52D3B4ZBNHPXS4C