N-acetyl-L-cysteine/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on all-cause mortality
StrongEvidence strength: strong. Randomised human trials or their synthesis, with the effect's size and interval recorded and no recorded weakness outstanding.FindingNull resultreplicated ×1“Results from 17 RCTs including 1,737 patients yielded a non-statistically significant difference between NAC and SoC on the reduction of mortality (RR 0.71, 95% CI 0.40 to 1.25; events (NAC:20/870, SoC:33/867); I2 = 0%; p = 0.23).”
Quoted verbatim from N-acetylcysteine use among patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized trials.. - Study
- meta-analysis
- Participants
- 1,737
- Population
- Adults undergoing on-pump or off-pump cardiac surgery, 17 randomised trials pooled, NAC added to standard of care versus standard of care with or without placebo; routes pooled (intravenous, cardioplegia, oral)
Effect 0.71 risk ratio, 95% CI 0.4 to 1.25
N-acetylcysteine use among patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized trials.2019PMID:31071081Permalink
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- Everything the graph holds on N-acetyl-L-cysteine
- Every compound studied against All-cause mortality
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To cite this finding: https://catalystproject.ai/e/01M4Q56EGBHCJM6V8M156XE8CE