L-leucine/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases body weight gain over a feeding or growth period
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Feeding of HFMP and HFL resulted in a lower body weight gain compared to HF due to a reduced fat mass accumulation.”
Quoted verbatim from Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle.. - Study
- animal · not in humans
- Duration
- 5 months
- Dose
- 50 g/kg diet L-leucine
- Population
- Male C57BL/6JRj mice on a 40 energy% high-fat diet; HFL arm is the high-fat diet with 50 g/kg L-leucine added, compared with unsupplemented high-fat diet (both 140 g/kg casein); 20-week feeding
Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle.2022PMID:35418570Permalink
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- Every compound studied against Body weight gain over a feeding or growth period
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To cite this finding: https://catalystproject.ai/e/01M4PSZHS981W45FWAANNQYDVJ