L-ascorbic acid/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases organism lifespan
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“Treatment with 1 mM vitamin C also significantly shortened the lifespan of both isp-1 and nuo-6 mutants without affecting the wild type (Table S1).”
Quoted verbatim from A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans.. - Study
- animal · not in humans
- Dose
- 1 mM in nematode growth medium
- Population
- Long-lived Caenorhabditis elegans mitochondrial mutants isp-1(qm150) and nuo-6(qm200), raised from hatching on plates containing 1 mM vitamin C; wild-type animals were reported unaffected
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans.2010PMID:21151885Permalink
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To cite this finding: https://catalystproject.ai/e/01M4PSYK6Q762KPGSB9B2V9YDN