tirzepatide/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases total cholesterol (TC)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“All three doses of tirzepatide significantly decreased TC: −0.25 mmol/L(95% CI:−0.34, −0.15; P <0.00001, high certainty) for 5 mg, −0.30 mmol/L(95% CI:−0.40, −0.20;P <0.00001, high certainty) for 10 mg, and −0.37 mmol/L(95% CI:−0.49, −0.24; P < 0.00001, moderate certainty) for 15 mg.”
Quoted verbatim from Efficacy and safety of once-weekly tirzepatide for weight management compared to placebo: An updated systematic review and meta-analysis including the latest SURMOUNT-2 trial.. - Study
- meta-analysis
- Dose
- 5, 10 and 15 mg once weekly
- Population
- Adults with or without type 2 diabetes in placebo-controlled trials, 12 to 72 weeks; all three doses
Efficacy and safety of once-weekly tirzepatide for weight management compared to placebo: An updated systematic review and meta-analysis including the latest SURMOUNT-2 trial.2024PMID:38850440Industry fundedPermalink
Keep reading
- Everything the graph holds on tirzepatide
- Every compound studied against Total cholesterol (TC)
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M4PR6JSXH2A09B9HBDXBZ408