sodium hydrogencarbonate/Finding
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Increases duration of mechanical ventilation
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“However, SBIC was associated with significant increases in the duration of ventilation (WMD = 0.64 hours; 95% CI = 0.16 to 1.11 hours; P = 0.008; Figure 6), ICU length of stay (WMD = 2.06 days; 95% CI = 0.54 to 3.58 days; P = 0.008; Figure 7), and incidence of alkalemia (RR = 2.21; 95% CI = 1.42 to 3.42; P < 0.001; Additional file 4).”
Quoted verbatim from Sodium bicarbonate in the prevention of cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis.. - Study
- meta-analysis
- Dose
- intravenous bolus plus continuous infusion, regimens varied across trials
- Population
- Adults undergoing cardiac surgery with cardiopulmonary bypass, most with pre-existing renal impairment or at risk of acute kidney injury; secondary endpoint pooled from four randomized trials
Effect 0.64 mean difference, 95% CI 0.16 to 1.11
Sodium bicarbonate in the prevention of cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis.2014PMID:25212718Permalink
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To cite this finding: https://catalystproject.ai/e/01M4PPSYX81HWG4YMBFZVRQG2P