L-cysteine/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on reduced glutathione concentration
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The CYS and ISO group means were not different for total glutathione, GSH, and GSH:GSSG, neither at enrollment nor infusion day (Table 2).”
Quoted verbatim from Effect of High-Dose Cysteine Supplementation on Erythrocyte Glutathione: A Double-Blinded, Randomized Placebo-Controlled Pilot Study in Critically Ill Neonates.. - Study
- RCT
- Dose
- cysteine-HCl 121 mg/kg/day in parenteral nutrition with sodium acetate 2 mEq/kg/day
- Population
- Critically ill neonates on mechanical ventilation and parenteral nutrition (SNAP > 10); intracellular erythrocyte GSH at enrollment and on infusion day, about study day 7; comparator is isonitrogenous additional parenteral amino acids without cysteine
Effect of High-Dose Cysteine Supplementation on Erythrocyte Glutathione: A Double-Blinded, Randomized Placebo-Controlled Pilot Study in Critically Ill Neonates.2016PMID:25139979Permalink
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- Everything the graph holds on L-cysteine
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To cite this finding: https://catalystproject.ai/e/01M4PEGAZD5PE7EXTXWF7TM0JM