L-citrulline/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on sequential Organ Failure Assessment (SOFA) total score
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“Overall, there was no significant difference in organ dysfunction as assessed by the SOFA score on day 7 after enrollment (4 [IQR, 2-6] in the L-citrulline group vs. 4 [IQR, 2-7] in the placebo group; Mann‒Whitney U test, p = 0.9).”
Quoted verbatim from Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial.. - Study
- RCT
- Dose
- 5 g enteral L-citrulline every 12 h for 5 days versus isonitrogenous, isocaloric placebo
- Population
- Mechanically ventilated medical ICU adults without sepsis or septic shock, four French ICUs
Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial.2023PMID:37784110Permalink
Keep reading
- Everything the graph holds on L-citrulline
- Every compound studied against Sequential Organ Failure Assessment (SOFA) total score
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M4PE83V6NW4311R3QVNY5HMF