aspartame/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Inhibits ALPI
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“In the bowel loop model, IAP activity was significantly (p = 0.02) reduced in mice that had ASP instilled into the loops compared with saline controls (0.2 ± 0.03 vs 0.4 ± 0.24).”
Quoted verbatim from Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice.. - Study
- animal · not in humans
- Dose
- 34 mg/kg instilled into the bowel loop
- Population
- Male mice, isolated 6-cm small-bowel loop injected with aspartame solution or saline, luminal contents assayed after 3 h
Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice.2017PMID:27997218Permalink
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To cite this finding: https://catalystproject.ai/e/01M45ZC94JNX69V5BCTCCWK8QR