duloxetine/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases visual analogue scale pain intensity
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“Pooled data shows that duloxetine can reduce postoperative VAS at movement (MD = −1.08; 95% CI, [−1.45–−0.7]; P <.05. Fig. 5).”
Quoted verbatim from Effect of duloxetine on pain relief after total knee arthroplasty: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Adults after a first total knee arthroplasty; six pooled randomised trials of perioperative duloxetine versus placebo; pain on movement pooled across postoperative timepoints from 24 hours to 5 days
Effect -1.08 mean difference, 95% CI -1.45 to -0.7
Effect of duloxetine on pain relief after total knee arthroplasty: A meta-analysis of randomized controlled trials.2023PMID:36897714Permalink
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To cite this finding: https://catalystproject.ai/e/01M45Z2Q9ADNAR7601880ZQ1XT