berberine/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases body mass
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×3“These results showed at 20 weeks the body weight significantly increased in HF group compared with NCD group (P<0.01), whereas BBR significantly suppressed body weight of mice with a high-fat diet in a dose-dependent manner (P<0.01).”
Quoted verbatim from Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway.. - Study
- animal · not in humans
- Dose
- 25 or 100 mg/kg daily by gavage, from 14 to 20 weeks of age
- Population
- Male C57BL/6J mice fed a high-fat diet; berberine 25 and 100 mg/kg versus saline gavage, body weight at 20 weeks of age
Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway.2021PMID:34421358Permalink
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To cite this finding: https://catalystproject.ai/e/01M45T4NSR3TKBSAFC4HBQXT1A