trazodone/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on pittsburgh Sleep Quality Index global score
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“For example, between baseline and 1-month, mean PSQI scores decreased 2.9 and 3.9 points among those randomized to placebo and trazodone, respectively; the difference in mean change was not significant (p =.145).”
Quoted verbatim from Trazodone for sleep disturbance during methadone maintenance: a double-blind, placebo-controlled trial.. - Study
- RCT
- Duration
- 4 weeks
- Dose
- 50 mg capsules, 1-3 at bedtime as needed, 50-150 mg
- Population
- Methadone-maintained adults with sleep complaints (baseline PSQI of 6 or higher); trazodone 50 mg capsules self-titrated at bedtime to 50-150 mg, against identical placebo capsules, for one month; all received a sleep hygiene brochure
Trazodone for sleep disturbance during methadone maintenance: a double-blind, placebo-controlled trial.2012PMID:21798674Permalink
Keep reading
- Everything the graph holds on trazodone
- Every compound studied against Pittsburgh Sleep Quality Index global score
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M45P1D7D8JMHDHR8X20F184C