tirzepatide/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases body mass
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×2“Compared with placebo, once‐weekly tirzepatide led to a substantial decrease in the percentage change in body weight, with an MD of −16.32% and a 95% CI of −18.35 to −14.29 (p < 0.0001).”
Quoted verbatim from Efficacy and Safety of Tirzepatide on Weight Loss in Patients Without Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Dose
- 5, 10 or 15 mg or maximum tolerated dose, once weekly
- Population
- Adults with overweight or obesity without diabetes, six placebo-controlled randomised trials of 18 to 88 weeks (five phase 3 SURMOUNT trials and one phase 1 trial)
Effect -16.32 mean difference, 95% CI -18.35 to -14.29
Efficacy and Safety of Tirzepatide on Weight Loss in Patients Without Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2025PMID:40510020Permalink
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- Everything the graph holds on tirzepatide
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To cite this finding: https://catalystproject.ai/e/01M45MMWQPXZ6KXSVASB57SB06