all-cis-5,8,11,14,17-icosapentaenoic acid/Finding
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Decreases all-cause mortality
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“The incidence of postinfarct mortality was significantly lower in the MI+EPA group than in the MI+PBS group (59.3% vs 41.2%, P=0.0361).”
Quoted verbatim from Long-Term Administration of Eicosapentaenoic Acid Improves Post-Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization.. - Study
- animal · not in humans
- Duration
- 8 weeks
- Dose
- EPA ethyl ester (more than 99% purity) 1 g/kg/day by oral gavage, once daily for 4 weeks before and 4 weeks after infarction; control received PBS by gavage
- Population
- Male 10-week-old C57BL/6J mice with myocardial infarction induced by left coronary artery ligation, followed 28 days after infarction
Long-Term Administration of Eicosapentaenoic Acid Improves Post-Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization.2017PMID:28223437Permalink
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- Every compound studied against All-cause mortality
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To cite this finding: https://catalystproject.ai/e/01M45EJW74FGMZ4AKR2D53W62Z