calciol/Finding
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Activates TREM2
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.Finding“Functionally, cholecalciferol induced TREM2-dependent signaling in human, rat, and mouse cells.”
Quoted verbatim from Cholecalciferol (vitamin D3) is an agonist of the Alzheimer's disease-associated immune receptor TREM2.. - Study
- in vitro · not in humans
- Population
- human, rat, and mouse macrophage and microglial cell cultures
Cholecalciferol (vitamin D3) is an agonist of the Alzheimer's disease-associated immune receptor TREM2.2026PMID:41825226Permalink
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To cite this finding: https://catalystproject.ai/e/01M3J5YB11KBA4KV56FWMS8E1V