glucosamine/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on WOMAC pain subscale
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“As for WOMAC pain scores (Fig., the summarized effect size was − 0.04 ([95% CI] − 0.13, 0.06), suggesting a favorable but not significant effect of glucosamine on knee pain as measured by WOMAC.”
Quoted verbatim from Effects of glucosamine in patients with osteoarthritis of the knee: a systematic review and meta-analysis.. - Study
- meta-analysis
- Dose
- pooled across trials: five used a sulfate salt of glucosamine (two of them Rottapharm/Madaus crystalline glucosamine sulfate), six used the hydrochloride salt, one used N-acetylated glucosamine, unclear for the rest; 1500 mg/day in most studies per the Discussion, per-trial doses not tabulated in Table 1
- Population
- Adults with knee osteoarthritis in randomised placebo-controlled trials published between 2003 and 2016; the pooled trials include both glucosamine given alone and commercial supplements combining glucosamine with other components, chondroitin among them.
Effect -0.04 standardised mean difference, 95% CI -0.13 to 0.06
Effects of glucosamine in patients with osteoarthritis of the knee: a systematic review and meta-analysis.2018PMID:29713967Permalink
Keep reading
- Everything the graph holds on glucosamine
- Every compound studied against WOMAC pain subscale
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M1D70714XKM73RV450B962P0