melatonin/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Increases total antioxidant capacity
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“The meta-analysis indicated that melatonin supplementation considerably lowered serum MDA levels (WMD: −1.54 μmol/L, 95% CI: −2.07, −1.01) and markedly increased serum TAC levels (WMD: 0.15 mmol/L, 95% CI: 0.08, 0.22) in the melatonin-treated group versus the untreated group.”
Quoted verbatim from Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.. - Study
- meta-analysis
- Population
- adults, pooled across 63 RCTs of melatonin supplementation across mixed clinical populations (including metabolic syndrome, chronic kidney disease, PCOS, COVID-19, multiple sclerosis, type 2 diabetes, and other conditions)
Effect 0.15 mean difference, 95% CI 0.08 to 0.22
Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.2025PMID:41515249Permalink
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To cite this finding: https://catalystproject.ai/e/01M1C9BSXT1N50TGMQ17C0QF2G