melatonin/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on HOMA-IR
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“No significant effects of melatonin were found on HOMA-IR (WMD: 0.15, 95% CI: −0.18, 0.48), serum FI levels (WMD: 0.49 µIU/mL, 95% CI: −1.08, 2.05), or HbA1c (WMD: −0.22%, 95% CI: −0.66, 0.21).”
Quoted verbatim from Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.. - Study
- meta-analysis
- Population
- adults, pooled across 63 RCTs of melatonin supplementation across mixed clinical populations (including metabolic syndrome, chronic kidney disease, PCOS, COVID-19, multiple sclerosis, type 2 diabetes, and other conditions)
Effect 0.15 mean difference, 95% CI -0.18 to 0.48
Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.2025PMID:41515249Permalink
Keep reading
- Everything the graph holds on melatonin
- Every compound studied against HOMA-IR
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M1C9BQJ71H9WXKHHGF81KZTN