curcumin/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on serum creatinine concentration
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“A comparison of aspartate transaminase, alanine transaminase, and creatinine levels revealed no significant differences between the curcumin and placebo groups.”
Quoted verbatim from Curcumin Attenuates Liver Steatosis via Antioxidant and Anti-Inflammatory Pathways in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial.. - Study
- RCT
- Dose
- Oral ethanolic Curcuma longa rhizome extract standardised to 75-85% total curcuminoids, 250 mg curcuminoids per capsule, three capsules twice daily (1500 mg curcuminoids/day) for 12 months
- Population
- Obese adults with type 2 diabetes mellitus managed on metformin (age >=35 y, BMI >=23 kg/m2, HbA1c <6.5%), Nakhon Nayok, Thailand; 227 randomised, per-protocol analysis and the analysed count is not reported in the paper; prespecified safety/adverse-effect assessment, not an efficacy endpoint (declared primary outcome: liver steatosis by controlled attenuation parameter)
Curcumin Attenuates Liver Steatosis via Antioxidant and Anti-Inflammatory Pathways in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial.2025PMID:41096556Industry fundedPermalink
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To cite this finding: https://catalystproject.ai/e/01M0Q4SXTT3TJ1E8JTCFSCFWCP