curcumin/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Increases glutathione peroxidase activity
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“Compared to the placebo group, curcumin supplementation significantly enhanced antioxidant defenses, as evidenced by increased levels of total antioxidant capacity (TAC), glutathione peroxidase (GPx), and superoxide dismutase (SOD) activity at 3, 6, 9, and 12 months.”
Quoted verbatim from Curcumin Attenuates Liver Steatosis via Antioxidant and Anti-Inflammatory Pathways in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial.. - Study
- RCT
- Duration
- 12 months
- Dose
- Oral ethanolic Curcuma longa rhizome extract standardised to 75-85% total curcuminoids, 250 mg curcuminoids per capsule, three capsules twice daily (1500 mg curcuminoids/day) for 12 months
- Population
- Obese adults with type 2 diabetes mellitus managed on metformin (age >=35 y, BMI >=23 kg/m2, HbA1c <6.5%), Nakhon Nayok, Thailand; 227 randomised, per-protocol analysis and the analysed count is not reported in the paper; secondary endpoint (declared primary outcome: liver steatosis by controlled attenuation parameter on transient elastography); GPx by RANSEL colorimetric assay
Curcumin Attenuates Liver Steatosis via Antioxidant and Anti-Inflammatory Pathways in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial.2025PMID:41096556Industry fundedPermalink
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To cite this finding: https://catalystproject.ai/e/01M0Q4SW56MPTQED3SB0SDF9JB