tooth agenesis, selective, X-linked, 1
Findings
No curated finding names tooth agenesis, selective, X-linked, 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any tooth agenesis in which the cause of the disease is a mutation in the EDA gene.
Definition from the Mondo Disease Ontology (MONDO:0010741), read 2026-09-29. CC BY 4.0.
- Inheritance
- X-linked dominant inheritance
HPO, annotations 2026-09-02
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Agenesis of lateral incisorHPOHP:0200153
- 5 of 5 reported patients · Male
- Aplasia of the maxillaHPOHP:0010667
- 5 of 5 reported patients · Male
- HypodontiaHPOHP:0000668
- 5 of 5 reported patients · Male
- Agenesis of molarHPOHP:0011054
- 9 of 10 reported patients · Male
- Agenesis of premolarHPOHP:0011051
- 9 of 10 reported patients · Juvenile onset · Male
- Heat intoleranceHPOHP:0002046
- 0 of 5 reported patients · Male
- Respiratory tract infection
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- EDAHGNC:3157
- Definitive · G2P · X-linked · 2017
- Strong · Labcorp Genetics (formerly Invitae) · X-linked · 2021
Where it sits
Other names
4 names
Resolves to: tooth agenesis, selective, X-linked, 1
- Also called
- EDA tooth agenesishypodontia/oligodontia, X-linked, 1STHAGX1tooth agenesis caused by mutation in EDA