infertility disorder
Findings
No curated finding names infertility disorder yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues.
Definition from the Mondo Disease Ontology (MONDO:0005047), read 2026-09-29. CC BY 4.0.
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, hp/releases/2026-09-01.
- InfertilityMondoHP:0000789
Genes
5 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- HGNC:43638HGNC:43638
- Strong · PanelApp Australia · Semidominant · 2025
- HGNC:20438HGNC:20438
- Moderate · PanelApp Australia · Autosomal recessive · 2025
- SPATA22HGNC:30705
- Moderate · Ambry Genetics · Autosomal recessive · 2024
- SYCP3HGNC:18130
- Moderate · PanelApp Australia · Autosomal dominant · 2025
- RABL2AHGNC:9799
- Limited · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
4 names
Resolves to: infertility disorder
- Also called
- fertility disordersinfertileSterilesterility