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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
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DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

Disease

prolymphocytic leukemia

MONDO:0001023Mondo

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Findings

No curated finding names prolymphocytic leukemia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

A mature B- or T- cell leukemia with progressive clinical course. It is characterized by the presence of medium-sized lymphocytes with visible nucleoli (prolymphocytes) in the peripheral blood, bone marrow, and spleen.

Definition from the Mondo Disease Ontology (MONDO:0001023), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: acute lymphoblastic leukemia
chronic leukemia
Narrower terms (3): B-cell prolymphocytic leukemia
splenic manifestation of prolymphocytic leukemia
T-cell prolymphocytic leukemia

Other names

4 names

Resolves to: prolymphocytic leukemia

Also called: prolymphocytic leukaemia (B or T-cell)prolymphocytic leukaemia (B or T)prolymphocytic leukemia (B or T-cell)prolymphocytic leukemia (B or T)