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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

Disease

T-cell prolymphocytic leukemia

MONDO:0019468Mondo

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Findings

No curated finding names T-cell prolymphocytic leukemia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

A slow-growing type of leukemia (blood cancer) in which too many lymphocytes are found in the bone marrow and/or blood. The T-cell is specified as the defective cell line.

Definition from the Mondo Disease Ontology (MONDO:0019468), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: mature T-cell and NK-cell non-Hodgkin lymphoma
prolymphocytic leukemia
T lymphoblastic leukemia/lymphoma
T-cell acute lymphoblastic leukemia

Other names

12 names

Resolves to: T-cell prolymphocytic leukemia

Also called: CLL, T-cellT cell chronic lymphocytic leukaemiaT cell chronic lymphocytic leukemiaT cell CLLT cell prolymphocytic leukaemiaT cell prolymphocytic leukemiaT prolymphocytic leukaemiaT prolymphocytic leukemiaT-cell chronic lymphocytic leukaemiaT-cell chronic lymphocytic leukemiaT-cell CLLT-PLL