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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
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DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

Disease

chronic leukemia

MONDO:0001014Mondo

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Findings

No curated finding names chronic leukemia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

A slowly progressing leukemia characterized by a clonal (malignant) proliferation of maturing and mature myeloid cells or mature lymphocytes. When the clonal cellular population is composed of myeloid cells, the process is called chronic myelogenous leukemia. When the clonal cellular population is composed of lymphocytes, it is classified as chronic lymphocytic leukemia, hairy cell leukemia, or T-cell large granular lymphocyte leukemia.

Definition from the Mondo Disease Ontology (MONDO:0001014), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: leukemia
Narrower terms (8): aggressive NK-cell leukemia
B-cell chronic lymphocytic leukemia
chronic eosinophilic leukemia
chronic monocytic leukemia
chronic myelomonocytic leukemia
chronic neutrophilic leukemia
prolymphocytic leukemia
T-cell large granular lymphocyte leukemia

Other names

4 names

Resolves to: chronic leukemia

Also called: chronic leukaemia (disease)chronic leukemia (disease)leukaemia (disease), chronicleukemia (disease), chronic