neurodegenerative disease
Findings
No curated finding names neurodegenerative disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function.
Definition from the Mondo Disease Ontology (MONDO:0005559), read 2026-09-29. CC BY 4.0.
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, hp/releases/2026-09-01.
- Cerebral degenerationMondoHP:0007313
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
- Narrower terms (22)
- brachial amyotrophic diplegia
- cerebellar degeneration
- cerebral degeneration
- choroidal sclerosis
- demyelinating disease
- eyelid degenerative disorder
- human prion disease
- hypertrophic olivary degeneration
- infantile bilateral striatal necrosis
- inherited neurodegenerative disorder
- Marchiafava-Bignami disease
- motor neuron disorder
- neuroaxonal dystrophy
- olivopontocerebellar atrophy
- primary progressive aphasia
- primary progressive apraxia of speech
- primary progressive freezing gait
- secondary Parkinson disease
- senile degeneration of brain
- superficial siderosis
- synucleinopathy
- tauopathy
Other names
4 names
Resolves to: neurodegenerative disease
- Also called
- brain degenerationcentral nervous system degenerative disordercentral nervous system neurodegenerative disorderdegenerative disorder of central nervous system