myelodysplastic syndrome
Findings
No curated finding names myelodysplastic syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)
Definition from the Mondo Disease Ontology (MONDO:0018881), read 2026-09-29. CC BY 4.0.
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
- Narrower terms (8)
- childhood myelodysplastic syndrome
- familial monosomy 7 syndrome
- myelodysplastic syndrome associated with isolated del(5q)
- myelodysplastic syndrome with excess blasts
- myelodysplastic syndrome with multilineage dysplasia
- myelodysplastic syndrome with ring sideroblasts
- myelodysplastic syndrome with single lineage dysplasia
- refractory anemia with excess blasts in transformation
Other names
16 names
Resolves to: myelodysplastic syndrome
- Also called
- dysmyelopoietic syndromehematopoeitic - myelodysplastic syndrome (MDS)MDSMDS-UMDS, unclassifiablemyelodysplasiamyelodysplastic neoplasmmyelodysplastic syndrome, somaticmyelodysplastic syndrome, unclassifiablemyelodysplastic syndrome/neoplasmMyelodysplastic Syndromesoligoblastic leukaemiaoligoblastic leukemiapreleukemiasmoldering leukemiasmouldering leukaemia