myelodysplastic syndrome with single lineage dysplasia
MONDO:0005272Mondo
Findings
No curated finding names myelodysplastic syndrome with single lineage dysplasia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A myelodysplastic syndrome characterized by dysplasia seen in at least 10% of the early cells of 1 cell type (either red blood cells, white blood cells, or megakaryocytes) in the bone marrow.
Definition from the Mondo Disease Ontology (MONDO:0005272), read 2026-09-29. CC BY 4.0.
Features
14 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Anemia of inadequate productionHPOHP:0010972
- Very frequent (80% to 99% of cases)
- MyelodysplasiaHPOHP:0002863
- Very frequent (80% to 99% of cases)
- Erythroid hypoplasiaHPOHP:0012133
- Frequent (30% to 79% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- Macrocytic anemiaHPOHP:0001972
- Frequent (30% to 79% of cases)
- Single lineage myelodysplasiaHPOHP:0012150
- Frequent (30% to 79% of cases)
- Abnormal cardiac ventricular functionHPOHP:0030872
- Occasional (5% to 29% of cases)
- Bone marrow hypocellularityHPOHP:0005528
- Occasional (5% to 29% of cases)
- DyspneaHPOHP:0002094
- Occasional (5% to 29% of cases)
- Normochromic anemiaHPOHP:0001895
- Occasional (5% to 29% of cases)
- Normocytic anemiaHPOHP:0001897
- Occasional (5% to 29% of cases)
- Abnormal bleedingHPOHP:0001892
- Very rare (1% to 4% of cases)
Show the remaining 2
- Decreased total neutrophil countHPOHP:0001875
- Very rare (1% to 4% of cases)
- ThrombocytopeniaHPOHP:0001873
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
Other names
5 names
Resolves to: myelodysplastic syndrome with single lineage dysplasia
- Also called
- MDS with single lineage dysplasiaMDS-SLDRArefractory anaemiarefractory anemia