myelodysplastic syndrome with ring sideroblasts
Findings
No curated finding names myelodysplastic syndrome with ring sideroblasts yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Acquired idiopathic sideroblastic anemia is one of a group of disorders known as the myelodysplastic syndromes (MDS) characterized by ineffective haemopoiesis affecting one or more blood cell lineages (myeloid, erythroid or megakaryocytic) leading to peripheral blood cytopenias and an increased risk of developing leukemia. Acquired idiopathic sideroblastic anemia is now more commonly referred to as refractory anemia with ringed sideroblasts or the acronym RARS.
Definition from the Mondo Disease Ontology (MONDO:0019157), read 2026-09-29. CC BY 4.0.
Features
28 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Anemia of inadequate productionHPOHP:0010972
- Very frequent (80% to 99% of cases)
- Refractory anemia with ringed sideroblastsHPOHP:0004828
- Very frequent (80% to 99% of cases)
- Erythroid hyperplasiaHPOHP:0012132
- Frequent (30% to 79% of cases)
- Megaloblastic erythroid hyperplasiaHPOHP:0200143
- Frequent (30% to 79% of cases)
- Normochromic anemiaHPOHP:0001895
- Frequent (30% to 79% of cases)
- Normocytic anemiaHPOHP:0001897
- Frequent (30% to 79% of cases)
Show the remaining 16
- HepatomegalyHPOHP:0002240
- Occasional (5% to 29% of cases)
- Hypochromic anemiaHPOHP:0001931
- Occasional (5% to 29% of cases)
- Hyposegmentation of neutrophil nucleiHPOHP:0011447
- Occasional (5% to 29% of cases)
- MyelodysplasiaHPOHP:0002863
- Occasional (5% to 29% of cases)
- SplenomegalyHPOHP:0001744
- Occasional (5% to 29% of cases)
- ThrombocytopeniaHPOHP:0001873
- Occasional (5% to 29% of cases)
Where it sits
Other names
14 names
Resolves to: myelodysplastic syndrome with ring sideroblasts
- Also called
- acquired idiopathic sideroblastic anaemiaacquired idiopathic sideroblastic anemiaAISAMDS with ring sideroblastsMDS-RSprimary acquired sideroblastic anaemiaprimary acquired sideroblastic anemiaPure sideroblastic AnaemiaPure sideroblastic AnemiaRARSrefractory Anaemia with Ring sideroblastsrefractory Anaemia with ringed sideroblastsrefractory Anemia with Ring sideroblastsrefractory Anemia with ringed sideroblasts