juvenile open angle glaucoma
Findings
No curated finding names juvenile open angle glaucoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Juvenile glaucoma (JG) is a rare autosomal dominant open angle glaucoma, characterized by early onset, severe elevation of intra ocular pressure of rapid progression, leading to optic nerve excavation and, when untreated, substantial visual impairment.
Definition from the Mondo Disease Ontology (MONDO:0020367), read 2026-09-29. CC BY 4.0.
Features
15 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal anterior chamber morphologyHPOHP:0000593
- Frequent (30% to 79% of cases)
- Abnormal optic nerve morphologyHPOHP:0000587
- Frequent (30% to 79% of cases)
- Abnormality iris morphologyHPOHP:0000525
- Frequent (30% to 79% of cases)
- Glaucomatous visual field defectHPOHP:0007854
- Frequent (30% to 79% of cases)
- Ocular hypertensionHPOHP:0007906
- Frequent (30% to 79% of cases)
- Open angle glaucomaHPOHP:0012108
- Frequent (30% to 79% of cases)
- Optic neuropathyHPOHP:0001138
- Frequent (30% to 79% of cases)
- Peripheral visual field lossHPOHP:0007994
- Frequent (30% to 79% of cases)
- Visual impairmentHPOHP:0000505
- Frequent (30% to 79% of cases)
- High myopiaHPOHP:0011003
- Occasional (5% to 29% of cases)
- Increased cup-to-disc ratioHPOHP:0012796
- Occasional (5% to 29% of cases)
- Temporal optic disc pallorHPOHP:0012511
- Occasional (5% to 29% of cases)
Show the remaining 3
- Central scotomaHPOHP:0000603
- Very rare (1% to 4% of cases)
- Retinal arterial occlusionHPOHP:0025326
- Very rare (1% to 4% of cases)
- Retinal venous occlusionHPOHP:0012636
- Very rare (1% to 4% of cases)
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
Other names
7 names
Resolves to: juvenile open angle glaucoma
- Also called
- childhood glaucoma (disease)glaucoma (disease) of childhoodglaucoma of childhoodJOAGjuvenile glaucomapaediatric glaucoma (disease)pediatric glaucoma (disease)