disseminated superficial actinic porokeratosis
Findings
No curated finding names disseminated superficial actinic porokeratosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Disseminated superficial actinic porokeratosis (DSAP) is the most common form of porokeratosis characterized by the presence of several small annular plaques with a distinctive keratotic rim found most commonly on sun-exposed areas of the skin, particularly the extremities.
Definition from the Mondo Disease Ontology (MONDO:0019212), read 2026-09-29. CC BY 4.0.
Features
4 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- PorokeratosisHPOHP:0200044
- Very frequent (80% to 99% of cases)
- Cutaneous photosensitivityHPOHP:0000992
- Frequent (30% to 79% of cases)
- PruritusHPOHP:0000989
- Occasional (5% to 29% of cases)
- Squamous cell carcinomaHPOHP:0002860
- Occasional (5% to 29% of cases)
Genes
5 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SART3HGNC:16860
- Moderate · Ambry Genetics · Autosomal dominant · 2020
- FDPSHGNC:3631
- Supportive · Orphanet · Autosomal dominant · 2021
- MVDHGNC:7529
- Supportive · Orphanet · Autosomal dominant · 2021
- MVKHGNC:7530
- Supportive · Orphanet · Autosomal dominant · 2021
- SLC17A9HGNC:16192
- Supportive · Orphanet · Autosomal dominant · 2021
Where it sits
- A kind of
- Narrower terms (7)
- porokeratosis 3, disseminated superficial actinic type
- porokeratosis 4, disseminated superficial actinic type
- porokeratosis 5, disseminated superficial actinic type
- porokeratosis 6, disseminated superficial actinic type
- porokeratosis 7, multiple types
- porokeratosis 8, disseminated superficial actinic type
- porokeratosis 9, multiple types