colorectal cancer
MONDO:0005575Mondo
Findings
No curated finding names colorectal cancer yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma.
Definition from the Mondo Disease Ontology (MONDO:0005575), read 2026-09-29. CC BY 4.0.
Genes
15 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TP53HGNC:11998
- Moderate · Ambry Genetics · Autosomal dominant · 2024
- ATG12HGNC:588
- Limited · Ambry Genetics · Autosomal dominant · 2024
- BLMHGNC:1058
- Limited · ClinGen · Autosomal dominant · 2024
- BUB1HGNC:1148
- Limited · Ambry Genetics · Autosomal dominant · 2022
- Limited · ClinGen · Autosomal dominant · 2023
- FANCCHGNC:3584
- Limited · Ambry Genetics · Autosomal dominant · 2022
- FLCNHGNC:27310
- Limited · Ambry Genetics · Autosomal dominant · 2023
- MCM8HGNC:16147
- Limited · Ambry Genetics · Autosomal dominant · 2024
- NPATHGNC:7896
- Limited · Ambry Genetics · Autosomal dominant · 2024
- PLA2G2AHGNC:9031
- Limited · Ambry Genetics · Autosomal dominant · 2024
- No Known Disease Relationship · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2018
- SETD6HGNC:26116
- Limited · Laboratory for Molecular Medicine · Unknown · 2020
- MUTYHHGNC:7527
- Disputed Evidence · ClinGen · Autosomal dominant · 2023
- DCCHGNC:2701
- No Known Disease Relationship · Labcorp Genetics (formerly Invitae) · Unknown · 2017
- DLC1HGNC:2897
- No Known Disease Relationship · Ambry Genetics · Unknown · 2018
- PTPRJHGNC:9673
- No Known Disease Relationship · Labcorp Genetics (formerly Invitae) · Unknown · 2018
- SRCHGNC:11283
- No Known Disease Relationship · Labcorp Genetics (formerly Invitae) · Unknown · 2017
Where it sits
- A kind of
Other names
34 names
Resolves to: colorectal cancer
- Also called
- cancer of colorectumcancer of large bowelcancer of large intestinecancer of the large bowelcolon cancer, advanced, somaticcolon cancer, somaticcolorectal cancer with chromosomal instability, somaticcolorectal cancer, autosomal dominant, somatic mutationcolorectal cancer, somaticcolorectal cancer, susceptibility to, autosomal dominant, somatic mutationcolorectum cancermalignant colorectal neoplasmmalignant colorectal tumormalignant colorectal tumourmalignant colorectum neoplasm