autoimmune hepatitis
MONDO:0016264Mondo
Findings
No curated finding names autoimmune hepatitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hepatitis caused by autoantibodies. Drugs, infections, and toxins may trigger the production of the autoantibodies against the liver parenchyma.
Definition from the Mondo Disease Ontology (MONDO:0016264), read 2026-09-29. CC BY 4.0.
Features
34 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Increased circulating IgG concentrationHPOHP:0003237
- Obligate (100% of cases)
- Increased circulating immunoglobulin concentrationHPOHP:0010702
- Obligate (100% of cases)
- Anti-liver cytosolic antigen type 1 antibody positivityHPOHP:0030909
- Very frequent (80% to 99% of cases)
- Anti-smooth muscle antibody positivityHPOHP:0003262
- Very frequent (80% to 99% of cases)
- Antineutrophil antibody positivityHPOHP:0003453
- Very frequent (80% to 99% of cases)
- Antinuclear antibody positivityHPOHP:0003493
- Very frequent (80% to 99% of cases)
- Elevated circulating hepatic transaminase concentrationHPOHP:0002910
- Very frequent (80% to 99% of cases)
- Liver kidney microsome type 1 antibody positivityHPOHP:0030908
- Very frequent (80% to 99% of cases)
- RosetteHPOHP:0031925
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- Anti-asialoglycoprotein receptor antibody positivityHPOHP:0032469
- Frequent (30% to 79% of cases)
- ArthralgiaHPOHP:0002829
- Frequent (30% to 79% of cases)
Show the remaining 22
- Chronic fatigueHPOHP:0012432
- Frequent (30% to 79% of cases)
- DepressionHPOHP:0000716
- Frequent (30% to 79% of cases)
- Spider hemangiomaHPOHP:0012522
- Frequent (30% to 79% of cases)
- Acute hepatitisHPOHP:0200119
- Occasional (5% to 29% of cases)
- AnxietyHPOHP:0000739
- Occasional (5% to 29% of cases)
- ArthritisHPOHP:0001369
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
- Narrower terms (7)