primary biliary cholangitis/primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome
MONDO:0034189Mondo
Findings
No curated finding names primary biliary cholangitis/primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Features
36 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Autoimmune antibody positivityHPOHP:0030057
- Very frequent (80% to 99% of cases)
- Interface hepatitisHPOHP:0032220
- Very frequent (80% to 99% of cases)
- Abnormal ductus choledochus morphologyHPOHP:0100889
- Frequent (30% to 79% of cases)
- Abnormal intrahepatic bile duct morphologyHPOHP:0011040
- Frequent (30% to 79% of cases)
- Anti-Gerbich phenotype 1 antibody positivityHPOHP:0034110
- Frequent (30% to 79% of cases)
- Anti-glycoprotein-210 antibody positivityHPOHP:0033562
- Frequent (30% to 79% of cases)
- Anti-hexokinase-1 antibody positivityHPOHP:0034114
- Frequent (30% to 79% of cases)
- Anti-Kelch like protein 12 antibody positivityHPOHP:0034115
- Frequent (30% to 79% of cases)
- Anti-MIT3 antibody positivityHPOHP:0034111
- Frequent (30% to 79% of cases)
- Anti-p53 antibody positivityHPOHP:0034107
- Frequent (30% to 79% of cases)
- Anti-Ro52/TRIM21 antibody positivityHPOHP:0034093
- Frequent (30% to 79% of cases)
- Anti-sp100 antibody positivityHPOHP:0034155
- Frequent (30% to 79% of cases)
Show the remaining 24
- Anti-Y-box protein-1 antibody positivityHPOHP:0034108
- Frequent (30% to 79% of cases)
- Antinuclear antibody positivityHPOHP:0003493
- Frequent (30% to 79% of cases)
- Elevated circulating hepatic transaminase concentrationHPOHP:0002910
- Frequent (30% to 79% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- Increased circulating IgG concentrationHPOHP:0003237
- Frequent (30% to 79% of cases)
- PruritusHPOHP:0000989
- Frequent (30% to 79% of cases)
Where it sits
- A kind of