seronegative autoimmune hepatitis
Findings
No curated finding names seronegative autoimmune hepatitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A form of autoimmune hepatitis characterized by the features of classic autoimmune hepatitis (i. e. clinical presentation as acute or chronic cryptogenic hepatitis, interface hepatitis on histological examination, elevated serum aspartate aminotransferase and alanine aminotransferase levels, hypergammaglobulinemia/elevated immunoglobulin G, therapeutic response to corticosteroids) in the absence of serum autoantibodies. Clinical manifestations include fatigue, malaise, arthralgia, jaundice, at later stages also signs of advanced chronic liver disease, such as spider nevi, caput medusae, splenomegaly, ascites, and palmar erythema. Presence of concurrent autoimmune diseases is frequently observed.
Definition from the Mondo Disease Ontology (MONDO:0035400), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
2 names
Resolves to: seronegative autoimmune hepatitis
- Also called
- autoantibody-negative autoimmune hepatitisSeronegative AIH