Compound
neurotensin-(1-8)
A peptide zwitterion that is the dizwitterionic form of neurotensin (1-8) having both carboxy groups deprotonated and the side-chains of L-lysyl and L-arginine protonated. It is the major species at pH 7.3.
Definition from ChEBI (CHEBI:147393), read 2026-09-23. CC BY 4.0.
CHEBI:147393ChEBI
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C46H71N13O14
- Mass
- 1030.151 g/mol
- Charge
- 0
- InChIKey
- ZJPYPJIAUOEHJV-LGYYRGKSSA-N
- SMILES
- CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)[O-])C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCC[NH3+])C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=[NH2+])C(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: neurotensin-(1-8) · Sources: Rhea
- neurotensin-(1-8) is a substrate of ACE2ProteinRhea RHEA:63572Inferred only
Reactions
1 reaction
neurotensin-(1-8)+waterneurotensin-(1-7)+L-arginine
Catalysed by ACE2
Reaction pageLeft to rightBalanced
Rhea RHEA:63572CC BY 4.0Reference data
Other names
5 names
Resolves to: neurotensin-(1-8)
- Also called
- L-Pyr-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg dizwitterionL-pyroglutamyl-L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-asparagyl-L-lysyl-L-prolyl-L-arginine dizwitterionL-pyroglutamyl-L-leucyl-L-tyrosyl-L-α-glutamyl-L-asparagyl-L-lysyl-L-prolyl-L-arginine dizwitterionPyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg dizwitterion
- Systematic name
- 5-oxo-L-prolyl-L-leucyl-L-tyrosyl-5-oxidanidyl-5-oxidanylidene-L-norvalyl-L-asparaginyl-6-azaniumyl-L-norleucyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-carboxylatobutyl]-L-prolinamide