Compound
mycophenolate
A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of mycophenolic acid.
Definition from ChEBI (CHEBI:62932), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C17H19O6
- Mass
- 319.333 g/mol
- Charge
- -1
- InChIKey
- HPNSFSBZBAHARI-RUDMXATFSA-M
- SMILES
- COc1c(C)c2c(c(O)c1C/C=C(C)CCC(=O)[O-])C(=O)OC2
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Regulatory determinations
LiverTox likelihood score DLiverTox
LiverTox Likelihood Score D — a possible hepatotoxin, single-to-few case reports. Chapter: "Mycophenolate". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not assessed
Statements
6 statements
6 statements · 1 reference database · Subject: mycophenolate · Sources: Rhea
- mycophenolate is converted to mycophenolate 7-O-beta-D-glucuronideCompoundRhea RHEA:63704Inferred only
- mycophenolate is converted to mycophenolic acid O-acyl-beta-D-glucuronideCompoundRhea RHEA:63700Inferred only
- mycophenolate is metabolised by UGT1A7ProteinRhea RHEA:63704Inferred only
- mycophenolate is metabolised by UGT1A8ProteinRhea RHEA:63704Inferred only
- mycophenolate is metabolised by UGT1A9ProteinRhea RHEA:63704Inferred only
- mycophenolate is metabolised by UGT2B7ProteinRhea RHEA:63700Inferred only
Reactions
5 reactions
mycophenolic acid O-acyl-beta-D-glucuronide+watermycophenolate+D-glucuronate+hydron
Catalysed by ABHD10
Reaction pageLeft to rightBalanced
Rhea RHEA:34179CC BY 4.0Reference data
mycophenolate+UDP-alpha-D-glucuronatemycophenolic acid O-acyl-beta-D-glucuronide+UDP
Catalysed by UGT2B7
Reaction pageLeft to rightBalanced
Rhea RHEA:63700CC BY 4.0Reference data
mycophenolate+UDP-alpha-D-glucuronatemycophenolate 7-O-beta-D-glucuronide+UDP+hydron
Catalysed by UGT1A9 or UGT1A7 or UGT1A8
Reaction pageLeft to rightBalanced
Rhea RHEA:63704CC BY 4.0Reference data
CHEBI:167447+watermycophenolate+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:66704CC BY 4.0Reference data
CHEBI:231832+S-adenosyl-L-methioninemycophenolate+S-adenosyl-L-homocysteine+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:81843CC BY 4.0Reference data
Other names
1 name
Resolves to: mycophenolate
- Systematic name
- (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate