Compound

an N-(acyl)-sphingosylphosphocholine

A class of sphingolipids found largely in the brain and other nervous tissue. They contain phosphocholine or phosphoethanolamine as their polar head group so therefore are the only sphingolipids classified as phospholipids.

Definition from MeSH (D013109), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:64583ChEBI

Open in the graph

Structure

2D depiction

Class: Structural class, not a single molecule
Formula: C9H19N2O6PR2
Mass: 282.231 g/mol
Charge: 0
SMILES: [1*][C@@H](O)[C@H](COP(=O)([O-])OCC[N+](C)(C)C)NC([2*])=O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

2 statements

2 statements · 1 reference database · Subject: an N-(acyl)-sphingosylphosphocholine · Sources: Rhea

Order

an N-(acyl)-sphingosylphosphocholine is a substrate of SMPD2ProteinRhea RHEA:45300Inferred only
an N-(acyl)-sphingosylphosphocholine is a substrate of SMPD3ProteinRhea RHEA:45300Inferred only

Reactions

5 reactions

an N-(acyl)-sphingosylphosphocholinean N-(acyl)-sphingosylphosphocholine
Transported by PITPNB
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:43776CC BY 4.0Reference data
an N-(acyl)-sphingosylphosphocholine+wateran N-acyl-sphingoid base+phosphocholine+hydron
Catalysed by SMPD2 or SMPD3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:45300CC BY 4.0Reference data
an N-(acyl)-sphingosylphosphocholine+ATP(4-)+wateran N-(acyl)-sphingosylphosphocholine+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCG1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:46468CC BY 4.0Reference data
an N-(acyl)-sphingosylphosphocholineCHEBI:143892+choline
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:60652CC BY 4.0Reference data
an N-acyl-sphingoid base+a 1,2-diacyl-sn-glycero-3-phosphocholinean N-(acyl)-sphingosylphosphocholine+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:81451CC BY 4.0Reference data

Other names

3 names

Resolves to: an N-(acyl)-sphingosylphosphocholine

Also called: Ceramide phosphocholineSMSphingomyelin