Compound
6-methylthiopurine
A thiopurine that is 9H-purine substituted by a methylsulfanyl group at position 6.
Definition from ChEBI (CHEBI:28279), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound
- Formula
- C6H6N4S
- Mass
- 166.209 g/mol
- Charge
- 0
- InChIKey
- UIJIQXGRFSPYQW-UHFFFAOYSA-N
- SMILES
- CSc1ncnc2ncnc12
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
4 statements
4 statements · 2 reference databases · Subject: 6-methylthiopurine · Sources: Human-GEM, Rhea
- 6-methylthiopurine is converted to mercaptopurineCompoundRhea RHEA:12609Inferred only
- mercaptopurine is converted to 6-methylthiopurineCompoundRhea RHEA:12609Inferred only
- 6-methylthiopurine is metabolised by TPMTProteinHuman-GEM MAR09504Inferred only
- 6-methylthiopurine is metabolised by TPMTProteinRhea RHEA:12609Inferred only
Reactions
2 reactions
6-methylthiopurine+proton+CHEBI:16680S-adenosyl-L-methionine+MAM02989c
Catalysed by TPMT
Reaction pageReversibleBalancedEC 2.1.1.67cytosol
Human-GEM MAR09504CC BY 4.0Reference data
mercaptopurine+S-adenosyl-L-methionine6-methylthiopurine+S-adenosyl-L-homocysteine+hydron
Catalysed by TPMT
Reaction pageDirection not assertedBalanced
Rhea RHEA:12609CC BY 4.0Reference data
Other names
6 names
Resolves to: 6-methylthiopurine
- Also called
- 6-(methylthio)-9H-purine6-(methylthio)purine6-methylmercaptopurineS-methyl-6-mercaptopurinethiopurine S-methylether
- Systematic name
- 6-(methylsulfanyl)-9H-purine