Compound

4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol

CHEBI:17813ChEBI

Structure

2D depiction · 3D model shown

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A generated conformer of 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C29H46O
Mass: 410.686 g/mol
Charge: 0
InChIKey: LFQXEZVYNCBVDO-PBJLWWPKSA-N
SMILES: [H][C@@]12CCC3=C(CC[C@@]4(C)C3=CC[C@]4([H])[C@H](C)CCC=C(C)C)[C@@]1(C)CC[C@H](O)C2(C)C
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

8 statements

8 statements · 2 reference databases · Subject: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol · Sources: Human-GEM, Rhea

Order

4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is converted to 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-olCompoundHuman-GEM MAR01484Inferred only
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is converted to 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-olCompoundHuman-GEM MAR00101Inferred only
lanosterol is converted to 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-olCompoundHuman-GEM MAR03598Inferred only
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is metabolised by CYP51A1ProteinRhea RHEA:75111Inferred only
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is metabolised by CYP51A1ProteinRhea RHEA:25286Inferred only
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is a substrate of LBRProteinHuman-GEM MAR01484Inferred only
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is a substrate of TM7SF2ProteinHuman-GEM MAR01484Inferred only
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is a substrate of TM7SF2ProteinHuman-GEM MAR00101Inferred only

Reactions

9 reactions

4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+proton+NADPH(4-)4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol+NADP(3-)
Catalysed by TM7SF2
Reaction pageLeft to rightBalancedEC 1.3.1.70GO:0005783
Human-GEM MAR00101CC BY 4.0Reference data
32-oxolanosterol+NADPH(4-)+dioxygen4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+formic acid+water+NADP(3-)
Catalysed by CYP51A1
Reaction pageLeft to rightBalancedEC 1.14.14.154GO:0005829
Human-GEM MAR01479CC BY 4.0Reference data
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+proton+NADPH(4-)4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol+NADP(3-)
Catalysed by LBR or TM7SF2
Reaction pageLeft to rightBalancedEC 1.3.1.70GO:0005829
Human-GEM MAR01484CC BY 4.0Reference data
2proton+lanosterol+3NADPH(4-)+3dioxygen4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+formic acid+4water+3NADP(3-)
Catalysed by CYP4F8
Reaction pageLeft to rightBalancedEC 1.14.14.1GO:0005829
Human-GEM MAR01497CC BY 4.0Reference data
2proton+lanosterol+3NADPH(4-)+3dioxygen4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+formic acid+4water+3NADP(3-)
Catalysed by CYP51A1
Reaction pageLeft to rightBalancedEC 1.14.14.154GO:0005783
Human-GEM MAR02200CC BY 4.0Reference data
carbon dioxide+3lanosterol34,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+2water+4MAM03357c
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR03598CC BY 4.0Reference data
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol+NADP(3-)4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+NADPH(4-)+hydron
Catalysed by TM7SF2 or LBR
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:18561CC BY 4.0Reference data
lanosterol+3reduced [NADPH--hemoprotein reductase]+3dioxygen4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+formate+3oxidized [NADPH--hemoprotein reductase]+4water+4hydron
Catalysed by CYP51A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:25286CC BY 4.0Reference data
32-oxolanosterol+reduced [NADPH--hemoprotein reductase]+dioxygen4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol+formate+oxidized [NADPH--hemoprotein reductase]+water+2hydron
Catalysed by CYP51A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:75111CC BY 4.0Reference data

Other names

9 names

Resolves to: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol

Also called: 4,4-Dimechol-8,14,24-trienol4,4-dimethylcholesta-8,11,24-trien-3beta-ol4,4-Dimethylcholesta-8,14,24-trienol4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol4,4-dimethylcholesta-8(9),14,24-trien-3β-olFF-MASFollicular fluid meiosis-activating sterolST 29:3;O
Systematic name: 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol