Compound
3',3'-cGAMP
An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of c-GMP-AMP; major species at pH 7.3.
Definition from ChEBI (CHEBI:71501), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C20H22N10O13P2
- Mass
- 672.401 g/mol
- Charge
- -2
- InChIKey
- RFCBNSCSPXMEBK-INFSMZHSSA-L
- SMILES
- Nc1nc(=O)c2ncn([C@@H]3O[C@@H]4COP(=O)([O-])O[C@H]5[C@@H](O)[C@H](n6cnc7c(N)ncnc76)O[C@@H]5COP(=O)([O-])O[C@H]4[C@H]3O)c2n1
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: 3',3'-cGAMP · Sources: Rhea
- 3',3'-cGAMP is transported by SLC19A1ProteinRhea RHEA:60468Inferred only
- 3',3'-cGAMP is transported by SLC46A2ProteinRhea RHEA:76415Inferred only
Reactions
5 reactions
GTP+ATP(4-)3',3'-cGAMP+2diphosphate(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:35647CC BY 4.0Reference data
3',3'-cGAMP+waterCHEBI:142752+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:58800CC BY 4.0Reference data
3',3'-cGAMP+5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide3',3'-cGAMP+5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide
Transported by SLC19A1
Reaction pageLeft to rightBalanced
Rhea RHEA:60468CC BY 4.0Reference data
3',3'-cGAMP+waterCHEBI:192497+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:72831CC BY 4.0Reference data
3',3'-cGAMP+nhydron3',3'-cGAMP+nhydron
Transported by SLC46A2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:76415CC BY 4.0Reference data
Where it reaches
1 system, 1 region, 1 tissue, 1 transporter route — routes, not measurements: transporters known to carry 3',3'-cGAMP are expressed there, and no source reports it arriving.
Loading the model…
Other names
4 names
Resolves to: 3',3'-cGAMP
- Also called
- 3',5'-cyclic GMP-AMP(2-)3',5'-cyclic GMP-AMP(2−)cGAMP(2-)cGAMP(2−)