What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- HADHAProteinUNIPROT:P40939substrate ofInferred only37 paths37 endpoints
- HADHBProteinUNIPROT:P55084substrate ofInferred only33 paths32 endpoints
- HSD17B4ProteinUNIPROT:P51659substrate ofInferred only27 paths27 endpoints
- ACAA1ProteinUNIPROT:P09110substrate ofInferred only24 paths24 endpoints
- EHHADHProteinUNIPROT:Q08426substrate ofInferred only21 paths21 endpoints
What the reference databases state
Statements
6 statements
6 statements · 1 reference database · Subject: (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA · Sources: Human-GEM
- (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA is converted to CHEBI:63544CompoundHuman-GEM MAR02391Inferred only
- (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR05379Inferred only
- (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR05379Inferred only
- (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR05378Inferred only
- (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA is a substrate of HADHBProteinHuman-GEM MAR05378Inferred only
- (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR05379Inferred only
Reactions
10 reactions
MAM00714c(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134GO:0005829
Human-GEM MAR02389CC BY 4.0Reference data
(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA+proton+NADPH(4-)CHEBI:63544+NADP(3-)
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR02391CC BY 4.0Reference data
MAM00714r(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA+water
Catalysed by ELOVL1
Reaction pageReversibleBalancedEC 2.3.1.199GO:0005783
Human-GEM MAR03465CC BY 4.0Reference data
CHEBI:1146900+water+NAD(+)+(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoACHEBI:15351+proton+NADH(2-)+arachidonoyl-CoA
Reaction pageLeft to rightBalancedGO:0005759
Human-GEM MAR05378CC BY 4.0Reference data
CHEBI:1146900+water+NAD(+)+(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoACHEBI:15351+proton+NADH(2-)+arachidonoyl-CoA
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05379CC BY 4.0Reference data
MAM03210m(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA
Catalysed by ECI1
Reaction pageLeft to rightBalancedEC 5.3.3.8GO:0005759
Human-GEM MAR05383CC BY 4.0Reference data
MAM03210x(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05402CC BY 4.0Reference data
CHEBI:76415(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA+water
Catalysed by HSD17B4
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:39327CC BY 4.0Reference data
(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA+NADPH(4-)+hydron(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA+NADP(3-)
Catalysed by TECR
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:39331CC BY 4.0Reference data
CHEBI:233776(2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:84851CC BY 4.0Reference data