Compound
2''-O-malonyl-ADP-D-ribose
A nucleotide-sugar oxoanion arising from deprotonation of the carboxy and diphosphate groups of 2''-O-malonyl-ADP-D-ribose; major species at pH 7.3.
Definition from ChEBI (CHEBI:87833), read 2026-09-23. CC BY 4.0.
CHEBI:87833ChEBI
Structure
- Class
- Organic compound, anion
- Formula
- C18H22N5O17P2
- Mass
- 642.34 g/mol
- Charge
- -3
- InChIKey
- MGHFTDDAANKBKA-IQSXCWIYSA-K
- SMILES
- Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)([O-])OC[C@H]2OC(O)[C@H](OC(=O)CC(=O)[O-])[C@@H]2O)[C@@H](O)[C@H]1O
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: 2''-O-malonyl-ADP-D-ribose · Sources: Rhea
- 2''-O-malonyl-ADP-D-ribose is a substrate of SIRT5ProteinRhea RHEA:47672Inferred only
Reactions
1 reaction
N(6)-malonyl-L-lysyl-[protein]+NAD(1-)+water2''-O-malonyl-ADP-D-ribose+nicotinamide+L-lysyl-[protein]
Catalysed by SIRT5
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:47672CC BY 4.0Reference data
Other names
2 names
Resolves to: 2''-O-malonyl-ADP-D-ribose
- Also called
- 2''-O-malonyl-ADP-ribose(3-)2''-O-malonyl-ADP-ribose(3−)