Compound

2-oxohexanoate

A medium-chain fatty acid anion that is the conjugate base of 2-oxohexanoic acid.

Definition from ChEBI (CHEBI:35177), read 2026-09-23. CC BY 4.0.

CHEBI:35177ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of 2-oxohexanoate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C6H9O3
Mass: 129.135 g/mol
Charge: -1
InChIKey: XNIHZNNZJHYHLC-UHFFFAOYSA-M
SMILES: CCCCC(=O)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

3 entities

3 entities reached.

0 reported hops3 assembled from the scaffold

What the reference databases state

Chemical structure

2-oxohexanoate has the functional parent hexanoateCompoundChEBI CHEBI:35177Inferred only

Statements

5 statements

5 statements · 1 reference database · Subject: 2-oxohexanoate · Sources: Rhea

Order

2-oxohexanoate is converted to (2R)-hydroxyhexanoateCompoundRhea RHEA:82491Inferred only
(2R)-hydroxyhexanoate is converted to 2-oxohexanoateCompoundRhea RHEA:82491Inferred only
2-oxohexanoate is a substrate of AADATProteinRhea RHEA:66060Inferred only
2-oxohexanoate is a substrate of AGXT2ProteinRhea RHEA:77363Inferred only
2-oxohexanoate is a substrate of LDHDProteinRhea RHEA:82491Inferred only

Reactions

8 reactions

L-2-aminohexanoate+2-oxoglutarate(2-)2-oxohexanoate+L-glutamate(1-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23600CC BY 4.0Reference data
L-2-aminohexanoate+dioxygen+water2-oxohexanoate+hydrogen peroxide+ammonium
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:61268CC BY 4.0Reference data
2-oxohexanoate+L-kynurenineL-2-aminohexanoate+kynurenate+water
Catalysed by AADAT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:66060CC BY 4.0Reference data
2-oxohexanoate+L-kynurenineL-2-aminohexanoate+CHEBI:58147
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:66064CC BY 4.0Reference data
CHEBI:133738+dioxygen2-oxohexanoate+hydrogen peroxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:69372CC BY 4.0Reference data
2-oxohexanoate+N(omega),N(omega)-dimethyl-L-arginineL-2-aminohexanoate+5-(3,3-dimethylguanidino)-2-oxopentanoate
Catalysed by AGXT2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:77363CC BY 4.0Reference data
(2R)-hydroxyhexanoate+FAD(3-)+hydron2-oxohexanoate+FADH2(2-)
Catalysed by LDHD
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:82491CC BY 4.0Reference data
(2R)-hydroxyhexanoate+NAD(1-)2-oxohexanoate+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:86071CC BY 4.0Reference data

Other names

3 names

Resolves to: 2-oxohexanoate

Also called: 2-ketocaproate2-ketohexanoate2-oxocaproate