knowcompounds2-oxoglutaric acid
Specimen compound organic compoundPlate I
2- oxoglutaric acid

- Formula
- C5H6O5
- Molar mass
- 146.098 g/mol
- ChEBI
- CHEBI:30915
- PubChem CID
- 51
- InChIKey
- KPGXRSRHYNQIFN-UHFFFAOYSA-N
↓ lowered
01 · the evidence, ordered
What the evidence says
- Very limited
2-oxoglutaric acid
8 compounds on the outer ring, not drawn
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02 · findings
What 2-oxoglutaric acid moved, and by how much
- Dose studied: as its paper gave it.
- Evidence strength: computed from the study. How it is computed
- Serum albuminMoved: lowersEvidence: Very limitedPaper: PMID 122972062002
- Who
- Patients after elective abdominal surgery receiving enteral nutrition for 5 days; both arms received enteral nutrition, the intervention arm's solution enriched with alpha-ketoglutarate
- Dose studied
- alpha-ketoglutarate enrichment of enteral formula, 5 days postoperatively; amount not stated in abstract
Transthyretin decreased by 25% in both groups, and albumin decreased significantly in the enriched group compared with the standard nutrition.”
Quoted verbatim from Alpha-ketoglutarate-supplemented enteral nutrition: effects on postoperative nitrogen balance and muscle catabolism.RCT · 5 daysPermalink
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No dose is advised.
- Dose studied: as its paper gave it.
- Evidence strength: computed from the study. How it is computed
03 · identity
Structure
- Charge
- 0
- SMILES
- O=C(O)CCC(=O)C(=O)O
04 · on the label · 125 products
Labelled products
Source: NIH DSLD · Ingredient: 2-oxoglutaric acid · 125 products · Declared amount per serving: 2–1,330 mg
61 labels state an amount64 do not
- All American EFXNytric EFX ProArginine Alpha-Ketoglutarate1 gper 1 tabletDSLD:629
- Allergy Research GroupNTFactor Advanced Physicians Formula300 mgper 5 tabletsDSLD:233555
- Allergy Research GroupNTFactor Healthy Aging50 mgper 2 tabletsDSLD:233416
- Beachbody NutritionalsActiVit Body Toning Formula2 mgper 2 tabletsDSLD:6828
- Beachbody NutritionalsActiVit Metabolism Formula2 mgper 2 tabletsDSLD:6824
- Beverly InternationalMuscle Synergy Lemonamount not statedper 27 gDSLD:332850
- Beyond HealthNatural Amino hGHamount not statedper 7 capsulesDSLD:306896
- BulkSupplements.comAAKG (L-Arginine Alpha-Ketoglutarate)739 mgper 2500 mgDSLD:312823
- BulkSupplements.comAAKG (L-Arginine Alpha-Ketoglutarate)739 mgper 2500 mgDSLD:312824
- BulkSupplements.comAAKG (L-Arginine Alpha-Ketoglutarate)739 mgper 2500 mgDSLD:312825
- BulkSupplements.comAAKG (L-Arginine Alpha-Ketoglutarate)739 mgper 2500 mgDSLD:312826
- Cardiovascular ResearchHepagen40 mgper 1 capsuleDSLD:304390
Show the remaining 113Show the first 12
Label record: NIH Office of Dietary Supplements · CC0
05 · the record
Sources
10
papers screened for 2-oxoglutaric acid
- admitted
- 1
- read and discarded
- 8
- not read yet
- 1
- Documented interactions
- None reported
Sources cited
1 paper · 1 finding