Compound
2-hydroxy-3-methoxy-17beta-estradiol
A 17β-hydroxy steroid that is 17β-estradiol in which the hydrogen at position 2 has been replaced by a hydroxy group and the phenolic hydrogen at position 3 has bee replaced by a methyl group.
Definition from ChEBI (CHEBI:89268), read 2026-09-23. CC BY 4.0.
CHEBI:89268ChEBI
Structure
- Class
- Organic compound
- Formula
- C19H26O3
- Mass
- 302.414 g/mol
- Charge
- 0
- InChIKey
- MMKYSUOJWFKECQ-SSTWWWIQSA-N
- SMILES
- [H][C@@]12CCc3cc(OC)c(O)cc3[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What the reference databases state
Chemical structure
- 2-hydroxy-3-methoxy-17beta-estradiol has the functional parent 17beta-estradiolCompoundChEBI CHEBI:89268Inferred only
Statements
1 statement
1 statement · 1 reference database · Subject: 2-hydroxy-3-methoxy-17beta-estradiol · Sources: Rhea
- 2-hydroxy-17beta-estradiol is converted to 2-hydroxy-3-methoxy-17beta-estradiolCompoundRhea RHEA:53092Inferred only
Reactions
1 reaction
2-hydroxy-17beta-estradiol+S-adenosyl-L-methionine2-hydroxy-3-methoxy-17beta-estradiol+S-adenosyl-L-homocysteine+hydron
Catalysed by COMT
Reaction pageLeft to rightBalanced
Rhea RHEA:53092CC BY 4.0Reference data
Other names
10 names
Resolves to: 2-hydroxy-3-methoxy-17beta-estradiol
- Also called
- (17beta)-3-methoxyestra-1(10),2,4-triene-2,17-diol(17β)-3-methoxyestra-1(10),2,4-triene-2,17-diol2-Hydroxyestradiol-3-methyl ether2,3,17beta-trihydroxy-1,3,5[10]-estratriene 2-methyl ether3-Methoxy-1,3,5[10]-estratriene-2,17beta-diol3-O-Methyl-2-hydroxyestradiol3,17beta-dihydroxy-2-methoxy-1,3,5[10]-estratrieneST 19:3;O3
- Systematic name
- 3-methoxyestra-1(10),2,4-triene-2,17beta-diol3-methoxyestra-1(10),2,4-triene-2,17β-diol